PRL-mediated STAT5B/ARRB2 pathway promotes the progression of prostate cancer through the activation of MAPK signaling

Abstract Previous study showed that higher expression of prolactin (PRL) was found in CRPC samples compared with hormone-naive prostate cancer (HNPC) and benign prostatic hyperplasia (BPH) samples.We further investigate the function of PRL in prostate cancer (PCa) and explored its downstream effects.We found heterogeneous expression of the PRLR in

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A bio-economic analysis of the hand-line and gillnet coastal fisheries of Pernambuco State, North-eastern Brazil

This paper presents a bio-economic analysis of the hand-line and gillnet coastal fisheries off Pernambuco State, north-eastern Brazil, in order to define management measures to support the decision-making process available to fisheries managers to reduce uncertainties about echofix spring reverb the sustainable development of the fisheries.The obje

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